Characterization of virus infections in experimental models and in clinical patients
Team:
Tytti Vuorinen, MD, M.Sc.D, Docent, Specialist in Clinical Microbiology
Department of Virology, University of Turku, Kiinamyllynkatu 13, FIN-20520 Turku.
Tel:+358-2-333 7473, Fax: +358-2-251 3303 tytti.vuorinen@utu.fi
Piritta Peri, FM, ins (M.Sc, B.Sc.) piritta.peri@utu.fi, Department of Virology
Michaela Nygårdas, FM, (M.Sc.) michaela.nygardas@abo.fi, Department of Virology
Ville Kytö, MD, M.Sc.D. ville.kyto@utu.fi, Department of Anatomy
Antti Saraste, MD, M.Sc.D. antti.saraste@utu.fi, Department of Clinical Physiology
Veijo Hukkanen, MD, Docent veijo hukkanen@utu.f, Department of Virology
Pekka Saukko, Professor pekka.saukko@utu.fi, Department of Forensic Medicine
The aims of the project are to study
1) pathogenenis of enterovirus induced myocarditis in mouse models
2) pathogenesis of virus infections in cell cultures with special emphasis on virus induced apoptosis and inhibition of virus replication by gene silencing (collaboration Academy prof. Dennis Bamford, Helsingin yliopisto) and cysteine proteinase inhibitors (collaboration prof. Magnus Abrahamson, University of Lund, Sweden)
3) human virus infections
a. etiology and mechanisms of human myocarditis
b. virus infections of central nervous system (collaboration prof. Pirkko Kotilainen, Department of Medicine and MD Laura Kupila, Department of Neurology, Turku University Central Hospital)
c. virus infections of respiratory tract (collaboration prof. Olli Ruuskanen and doc. Terho Heikkinen, Department of Pediatrics, Turku University Central Hospital