Cariology
Research in the department currently focuses on the following topics:
1. host defence systems in the oral cavity
2. saliva, probiotics and gut microflora
3. immunology of dental caries
4. hyposalivation and xerostomia
5. applications of bioactive glass in endodontology
6. female sex steroids, saliva and dental caries
Selected publications 2003-2006:
Eliasson L, Carlén A, Laine M, Birkhed D. Minor gland and whole saliva in postmenopausal women using a low potency oestrogen (oestriol). Arch Oral Biol 48, 511-517, 2003
Haukioja A, Ihalin R, Loimaranta V, Lenander M, Tenovuo J. Sensitivity of Helicobacter pylori to an innate defence mechanism, the lactoperoxidase system, in buffer and in human whole saliva. J Med Microbiol 53, 855-860, 2004
Ihalin R, Loimaranta V, Tenovuo J. Origin, structure and biological activities of peroxidases in human saliva. Arch Biochem Biophys 445, 261-268, 2006
Haukioja A, Yli-Knuuttila H, Loimaranta V, Kari K, Ouwehand A, Meurman J H, Tenovuo J. Oral adhesion and survival of probiotic and other lactobacilli and bifidobacteria in vitro. Oral Microbiol Immunol 21, 326-332, 2006
Russell MW, Bobek LA, Brock JH, Hajishengallis G, Tenovuo J. Innate humoral defence factors. Chapter 5, ss 73-93. Kirjassa ?Mucosal Immunology? (toim. Mestecky J, Bienenstock J, Lamm ME, Mayer L, Strober W, McGhee JR), Academic Press/Elsevier, San Diego, USA, 2005
Sirén EK, Haapasalo M, Waltimo T, Orstavik D. In vitro antibacterial effect of calcium hydroxide combined with chlorhexidine or potassium iodide on Enterococcus faecalis. Eur J Oral Sci 112, 326-331, 2004
Waltimo T, Trope T, Haapasalo M, Orstavik D. Clinical efficacy of treatment procedures in endodontic infection control and one-year follow-up of periapical healing. J Endodontics 31, 863-866, 2005
Välimaa H, Savolainen S. Soukka T, Silvoniemi P. Mäkelä S, Kujari H, Gustafsson J-Å, Laine M. Estrogen receptor beta (Erb) is the predominant estrogen receptor subtype in human oral epithelium and salivary glands. J Endocrinol 180, 55-62, 2004